Mr Fry is clearly an exceptional and skilled surgeon with a warm and friendly manner


Mr Fry was exceptionally helpful and understanding


Mr Fry’s excellent surgery… made a difficult situation so much easier.

A private patient, August 2017

I owe you such a debt of gratitude over the last 4 years since my operation.

A Mouth Cancer patient, December 2017

You are saving lives!


Many thanks to Mr Fry and his team for their great and professional service.

A Private Patient, May 2018

I consider myself very lucky to have been directed to Mr Fry’s care… a caring and approachable consultant who inspires total confidence.

A Private patient, December 2017

You said you would look after me and you certainly did! I received simply first class treatment.

An NHS patient, August 2017

Thank you so much for your skill and kindness.

An NHS patient, August 2017

My Expertise

Mouth Cancers

When it comes to Mouth Cancer treatment, your best chance is your first chance.

As chair of the Head and Neck Team at Guy’s Hospital, Alastair diagnoses and treats over 100 cases of mouth cancer every year – with outcomes that cannot be bettered anywhere else in the world.

If you think you may have a mouth cancer, it’s vital that you see an appropriate specialist as soon as possible. Mouth cancers are relatively rare and sadly many patients have their treatment delayed because they have been falsely reassured by clinicians with little to no appropriate experience.

Previously the typical patient with a mouth cancer is someone who has been a smoker and consumed alcohol, but increasingly we are seeing patients who are younger and have no other risk factors. We would therefore advise you to seek an urgent opinion if you are concerned that you may have a mouth cancer.

If you are experiencing any of the following symptoms, you should seek an urgent review from a mouth cancer specialist:

  • A Persistent ulcer (that lasts 2 weeks or longer)
  • A lump in the mouth
  • Neck lumps
  • White or red patches in the mouth
  • Numbness affecting the mouth or lips
  • Mobile teeth
  • Difficulty swallowing
  • A change in voice or speech

It is well established that outcomes are significantly better if cancers are caught at an early stage and we would encourage you to make an appointment if you are concerned. It is also our experience that many patients have been worrying for some time about lesions in their mouth, and many can be immediately reassured by Alastair.

How Alastair can help you

Alastair is a highly-trained microvascular reconstructive surgeon, who since 2019 has performed more head and neck surgery than anyone else in the UK. His Guy’s Hospital & Cromwell team – the busiest and best in London – has a current free flap success rate at a staggering 98% as of Nov 2023.

Alastair and the team have managed to decrease the complication rates further than ever before, using the latest innovative techniques and highest quality precision surgery. He is now providing outcomes that cannot be bettered anywhere else in the world.

He is at the forefront of innovation of reconstructive techniques, including the use of 3D printers to reduce the impact of surgery. He has also presented at major international conferences across the world and has multiple publications. Alastair’s recent innovations have been to reduce side effects and improve outcomes for patients with head and neck cancer. These have included the development of scarless facial reconstruction and avoidance of neck scars.

As well as his work at Guy’s Hospital, he also has experience in treating very early cancers, or ‘pre-cancers’ (dysplasia) with laser surgery.

If you, or your referring doctor, suspect you may have a cancer, Alastair will usually be able to see you within just a few days, and perform all necessary tests within a week.

It should be noted that the above symptoms can be caused by other oral conditions. As a specialist in Oral and Maxillofacial Surgery, Alastair Fry has experience of managing a wide range of oral conditions and can advise you the best way to proceed.

The procedure

At your consultation, Alastair will take time to hear about the problems you’ve been having as well as perform an examination. Due to the extensive experience in a range of oral conditions in addition to mouth cancers, Alastair is often able to reassure and offer likely diagnosis at this point. Further tests such as biopsies and any scans can usually be performed at that time or at a time to suit.

In fact, we are now offering a one-stop clinic with same-day biopsy, MRI scans and Endoscopic examination if required.

In current treatment of mouth cancers, patients should expect to receive the best treatment outcomes in terms of survival whilst also maintaining the best possible quality of life in terms of appearance, speech and swallow.

If surgery is required this will be offered at the very best hospital in the UK for complex head and neck cancer surgery: The Cromwell Hospital.

The Cromwell is now firmly positioned as the highest-volume private head and neck cancer free flap centre in the UK. With that comes significant expertise in rehabilitation, including world-class Speech Therapy, Physiotherapy and Dietetics. This ensures that you will be completely supported throughout your care and subsequent follow up.

Early or ‘Pre-cancers’

Sometimes mouth cancers arise in areas of abnormal mouth lining which we term dysplasias. These typically appear as white, red or mixed patches in the mouth which may or may not be painful. These lesions are usually graded after biopsy from mild to severe and carry a significant risk of turning in to mouth cancers ( up to 50% for some severe dysplasias ).

The key thing is that these lesions can offer a window of opportunity to stop the development of mouth cancer by early removal. Alastair can offer laser treatment to remove these lesions which causes minimal side effects and is well tolerated by patients.

Mouth Cancer Surgery

Mouth cancer surgery usually involves the removal of the primary tumour within the mouth, removal of the glands in the neck which are at risk of harbouring cancer cells via a neck dissection or Sentinel node biopsy, and reconstruction of the defect to improve swallow and speech.